Proactive vaccination using multiviral Quartet Nanocages to elicit broad anti-coronavirus responses
Defending against future pandemics requires vaccine platforms that protect across a range of related pathogens. Nanoscale patterning can be used to address this issue. Here, we produce quartets of linked receptor-binding domains (RBDs) from a panel of SARS-like betacoronaviruses, coupled to a comput...
Main Authors: | Hills, RA, Tan, TK, Cohen, AA, Keeffe, JR, Keeble, AH, Gnanapragasam, PNP, Storm, KN, Rorick, AV, West, AP, Hill, ML, Liu, S, Gilbert-Jaramillo, J, Afzal, M, Napier, A, Admans, G, James, WS, Bjorkman, PJ, Townsend, AR, Howarth, MR |
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Format: | Journal article |
Language: | English |
Published: |
Nature Research
2024
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