External beam radiation therapy and enadenotucirev: Inhibition of the DDR and mechanisms of radiation-mediated virus increase
Ionising radiation causes cell death through the induction of DNA damage, particularly double-stranded DNA (dsDNA) breaks. Evidence suggests that adenoviruses inhibit proteins involved in the DNA damage response (DDR) to prevent recognition of double-stranded viral DNA genomes as cellular dsDNA brea...
Huvudupphovsmän: | , , , , , , , , , , , , , , , |
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Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
MDPI
2020
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