External beam radiation therapy and enadenotucirev: Inhibition of the DDR and mechanisms of radiation-mediated virus increase

Ionising radiation causes cell death through the induction of DNA damage, particularly double-stranded DNA (dsDNA) breaks. Evidence suggests that adenoviruses inhibit proteins involved in the DNA damage response (DDR) to prevent recognition of double-stranded viral DNA genomes as cellular dsDNA brea...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän: Pokrovska, TD, Jacobus, EJ, Puliyadi, R, Prevo, R, Frost, S, Dyer, A, Baugh, R, Rodriguez-Berriguete, G, Fisher, K, Giovanna, G, Herbert, K, Taverner, WK, Champion, BR, Higgins, G, Seymour, LW, Lei-Rossmann, J
Materialtyp: Journal article
Språk:English
Publicerad: MDPI 2020