A Bayesian cost-benefit approach to sample size determination and evaluation in clinical trials

<p>Current practice for sample size computations in clinical trials is largely based on frequentist or classical methods. These methods have the drawback of requiring a point estimate of the variance of treatment effect and are based on arbitrary settings of type I and II errors. They also do...

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Bibliographic Details
Main Author: Kikuchi, T
Other Authors: Gittins, J
Format: Thesis
Language:English
Published: 2011
Subjects: