A Bayesian cost-benefit approach to sample size determination and evaluation in clinical trials

A Bayesian cost-benefit approach to sample size determination and evaluation in clinical trials

<p>Current practice for sample size computations in clinical trials is largely based on frequentist or classical methods. These methods have the drawback of requiring a point estimate of the variance of treatment effect and are based on arbitrary settings of type I and II errors. They also do...

Полное описание

Библиографические подробности
Главный автор:	Kikuchi, T
Другие авторы:	Gittins, J
Формат:	Диссертация
Язык:	English
Опубликовано:	2011
Предметы:	Statistics (see also social sciences)

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