Conjugation, labelling and in vitro/in vivo assessment of an anti-VEGF monoclonal antibody labelled with niobium isotopes

Niobium-90 (90Nb) is a positron emitting radionuclide that exhibits attractive characteristics for use in the design and synthesis of radioimmunoconjugates. In the current study we have investigated 90Nb as a possible future isotope for immuno-PET. Prior to 90Nb in vivo studies, this paper describes...

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Bibliographic Details
Main Authors: De La Fuente, A, Radchenko, V, Tsotakos, T, Tsoukalas, C, Paravatou-Petsotas, M, Harris, AL, Köster, U, Rösch, F, Bouziotis, P
Format: Journal article
Language:English
Published: Springer Nature 2018