Commitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogeny
T lineage commitment occurs in a discrete, stage-specific manner during thymic ontogeny. Intrathymic precursor transfer experiments and the identification of CD4+8+ double-positive (DP), Vα14Jα18 natural T (iNKT) cells suggest that commitment to this lineage might occur at the DP stage. Nevertheless...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
National Academy of Sciences
2005
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