Commitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogeny
T lineage commitment occurs in a discrete, stage-specific manner during thymic ontogeny. Intrathymic precursor transfer experiments and the identification of CD4+8+ double-positive (DP), Vα14Jα18 natural T (iNKT) cells suggest that commitment to this lineage might occur at the DP stage. Nevertheless...
Principais autores: | , , , , |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado em: |
National Academy of Sciences
2005
|