Amplification of antibody production by phosphorothioate oligodeoxynucleotides.

A phosphorothioate oligodeoxynucleotide that is complementary (antisense) to the initiation region of the rev gene of HIV-1 causes hypergammaglobulinemia and splenomegaly in mice, and it induces B cell proliferation and differentiation in mouse spleen mononuclear cells (SMNCs) and human peripheral b...

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Detalhes bibliográficos
Principais autores: Branda, R, Moore, A, Lafayette, A, Mathews, L, Hong, R, Zon, G, Brown, T, McCormack, J
Formato: Journal article
Idioma:English
Publicado em: 1996