Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium.

While genome-wide association studies (GWAS) have primarily examined populations of European ancestry, more recent studies often involve additional populations, including admixed populations such as African Americans and Latinos. In admixed populations, linkage disequilibrium (LD) exists both at a f...

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Bibliographic Details
Main Authors: Pasaniuc, B, Zaitlen, N, Lettre, G, Chen, G, Tandon, A, Kao, W, Ruczinski, I, Fornage, M, Siscovick, D, Zhu, X, Larkin, E, Lange, L, Cupples, L, Yang, Q, Akylbekova, E, Musani, S, Divers, J, Mychaleckyj, J, Li, M, Papanicolaou, G, Millikan, R, Ambrosone, C, John, E, Bernstein, L, Zheng, W, Hu, J, Ziegler, R, Nyante, S, Bandera, E, Ingles, SA, Press, M, Chanock, S, Deming, S, Rodriguez-Gil, J, Palmer, C, Buxbaum, S, Ekunwe, L, Hirschhorn, J, Henderson, B, Myers, S, Haiman, C, Reich, D, Patterson, N, Wilson, J, Price, A
Format: Journal article
Language:English
Published: Public Library of Science 2011