Immune responses in interleukin-2-deficient mice.
The role of costimulatory signals in T cell induction was evaluated in mice lacking the interleukin-2 (IL-2) gene. In vitro secondary antiviral T cell responses were absent unless IL-2 was added, confirming the crucial role of IL-2 in vitro. In vivo, primary and secondary cytotoxic T cell responses...
Hlavní autoři: | , , , , , |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
1993
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