Immune responses in interleukin-2-deficient mice.

The role of costimulatory signals in T cell induction was evaluated in mice lacking the interleukin-2 (IL-2) gene. In vitro secondary antiviral T cell responses were absent unless IL-2 was added, confirming the crucial role of IL-2 in vitro. In vivo, primary and secondary cytotoxic T cell responses...

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Bibliografische gegevens
Hoofdauteurs: Kündig, T, Schorle, H, Bachmann, M, Hengartner, H, Zinkernagel, R, Horak, I
Formaat: Journal article
Taal:English
Gepubliceerd in: 1993