Regulation of intracellular pH in cancer cell lines under normoxia and hypoxia.
Acid-extrusion by active transport is important in metabolically active cancer cells, where it removes excess intracellular acid and sets the intracellular resting pH. Hypoxia is a major trigger of adaptive responses in cancer, but its effect on acid-extrusion remains unclear. We studied pH-regulati...
Hauptverfasser: | , , , |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2013
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