MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1

MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1

Matrix metalloproteinase 13 (MMP-13) degrades collagenous extracellular matrix and its aberrant activity associates with diseases such as arthritis, cancer, atherosclerosis and fibrosis. The wide range of MMP-13 proteolytic capacity suggests that it is a powerful, potentially destructive proteinase...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Yamamoto, K, Okano, H, Miyagawa, W, Visse, R, Shitomi, Y, Santamaria, S, Dudhia, J, Troeberg, L, Strickland, D, Hirohata, S, Nagase, H
स्वरूप: Journal article
प्रकाशित: Elsevier 2016

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