Membrane pore formation at protein-lipid interfaces.
Pore-forming proteins (PFPs) interact with lipid bilayers to compromise membrane integrity. Many PFPs function by inserting a ring of oligomerized subunits into the bilayer to form a protein-lined hydrophilic channel. However, mounting evidence suggests that PFPs can also generate 'proteolipidi...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2014
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