2ʹ-Deoxyadenosine 5ʹ-diphosphoribose is an endogenous TRPM2 superagonist
Transient receptor potential melastatin 2 (TRPM2), is a ligand-gated Ca2+-permeable non19 selective cation channel. While physiological stimuli, e.g. chemotactic agents, evoke controlled Ca2+ signals via TRPM2, pathophysiological signals, such as reactive oxygen species or genotoxic stress result in...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
Nature Publishing Group
2017
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