Hypoxia-activated tumor pathways of angiogenesis and pH regulation independent of anemia in head-and-neck cancer.

PURPOSE: Anemia is considered a major factor that counteracts the efficacy of radiotherapy, presumably because of reduced oxygen availability that leads to tumor hypoxia. Nevertheless, anemia is not the only factor defining oxygen availability, because a poor and/or immature vascular network may pr...

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Bibliographic Details
Main Authors: Koukourakis, M, Giatromanolaki, A, Sivridis, E, Pastorek, J, Karapantzos, I, Gatter, K, Harris, A
Format: Journal article
Language:English
Published: 2004