Human Purkinje in silico model enables mechanistic investigations into automaticity and pro-arrhythmic abnormalities

Cardiac Purkinje cells (PCs) are implicated in lethal arrhythmias caused by cardiac diseases, mutations, and drug action. However, the pro-arrhythmic mechanisms in PCs are not entirely understood, particularly in humans, as most investigations are conducted in animals. The aims of this study are to...

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Bibliographic Details
Main Authors: Trovato, C, Passini, E, Nagy, N, Varro, A, Abi-Gerges, N, Severi, S, Rodriguez, B
Format: Journal article
Language:English
Published: Elsevier 2020