Alpha-thalassaemia caused by a polyadenylation signal mutation.
Most eukaryotic messenger RNAs have the sequence AAUAAA 11-30 nucleotides from the 3'-terminal poly(A) tract. Since this is the only significant sequence homology in the 3' non-coding region it has been suggested that it may be a recognition site for enzymes involved in polyadenylation and...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1983
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