Alpha-thalassaemia caused by a polyadenylation signal mutation.

Most eukaryotic messenger RNAs have the sequence AAUAAA 11-30 nucleotides from the 3'-terminal poly(A) tract. Since this is the only significant sequence homology in the 3' non-coding region it has been suggested that it may be a recognition site for enzymes involved in polyadenylation and...

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Detalhes bibliográficos
Principais autores: Higgs, D, Goodbourn, SE, Lamb, J, Clegg, J, Weatherall, D, Proudfoot, N
Formato: Journal article
Idioma:English
Publicado em: 1983