Potential and limitations of a gamma 34.5 mutant of herpes simplex 1 as a gene therapy vector in the CNS.

Direct injection of viral vectors into the central nervous system has become a valuable technique for exploring the function of neurological systems and is a potential therapy for neural disease. To this end a number of herpes simplex virus (HSV)-derived vectors are currently being developed for the...

Full description

Bibliographic Details
Main Authors: McMenamin, M, Byrnes, A, Pike, F, Charlton, H, Coffin, R, Latchman, D, Wood, M
Format: Journal article
Language:English
Published: Nature Publishing Group 1998