Molecular dynamics studies of AChBP with nicotine and carbamylcholine: the role of water in the binding pocket.
The acetylcholine-binding protein (AChBP) is homologous to the ligand-binding domain of the nicotinic acetylcholine receptor (nAChR) and other members of the Cys-loop family of neurotransmitter receptors. The high-resolution X-ray structures of AChBP mean it has been used as a model from which to un...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2007
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