The role of p53 in hypoxia-induced apoptosis

<p>Tumour hypoxia is associated with resistance to therapy, increased aggressiveness and a poor patient prognosis. The tumour suppressor p53 causes apoptosis in response to hypoxia and therefore hypoxic tumours select for the loss of p53.</p><p>In this work was we have investigate...

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Bibliographic Details
Main Author: Poole, R
Other Authors: Hammond, E
Format: Thesis
Language:English
Published: 2010
Subjects: