The role of p53 in hypoxia-induced apoptosis
<p>Tumour hypoxia is associated with resistance to therapy, increased aggressiveness and a poor patient prognosis. The tumour suppressor p53 causes apoptosis in response to hypoxia and therefore hypoxic tumours select for the loss of p53.</p><p>In this work was we have investigate...
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Format: | Thesis |
Language: | English |
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2010
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