The pharmacological and anatomical substrates of the amphetamine response in the rat.

Bilateral 6-hydroxydopamine microinjections into the substantia nigra abolished both the locomotor and stereotyped responses to d-amphetamine in adult rats. The lesions resulted in a depletion of over 99 per cent of striatal tyrosine hydroxylase activity (indicating a near total lesion of the nigro...

Полное описание

Библиографические подробности
Главные авторы: Creese, I, Iversen, S
Формат: Journal article
Язык:English
Опубликовано: 1975