What can we learn about acid-base transporters in cancer from studying somatic mutations in their genes?

<p>Acidosis is a chemical signature of the tumour microenvironment that challenges intracellular pH homeostasis. The orchestrated activity of acid-base transporters of the solute-linked carrier (SLC) family is critical for removing the end-products of fermentative metabolism (lactate/H<sup&...

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Bibliographic Details
Main Authors: White, B, Swietach, P
Format: Journal article
Language:English
Published: Springer 2023