What can we learn about acid-base transporters in cancer from studying somatic mutations in their genes?

<p>Acidosis is a chemical signature of the tumour microenvironment that challenges intracellular pH homeostasis. The orchestrated activity of acid-base transporters of the solute-linked carrier (SLC) family is critical for removing the end-products of fermentative metabolism (lactate/H<sup&...

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Detalhes bibliográficos
Principais autores: White, B, Swietach, P
Formato: Journal article
Idioma:English
Publicado em: Springer 2023