DNA sequence driven machine learning for modelling replication timing

All human somatic cells copy their entire genome during mitotic replication, in the S-phase of the cell cycle. Replication timing (RT) is the temporal order of genome replication in S-phase and has been shown to have consistent global “profiles” across a wide range of tissues and diseases. We demon...

Full description

Bibliographic Details
Main Author: Ashford, J
Other Authors: Sahakyan, A
Format: Thesis
Language:English
Published: 2023
Subjects: