X-ray crystallography of agonist/antagonist-bound receptors.
Crystallographic analysis of the ligand-binding domains of nuclear hormone receptors (NR) has provided a unique insight into the molecular events that underlie the ligand-mediated control of their transcriptional activity. The technique relies on preparing milligram quantities of protein, growing th...
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| Format: | Journal article |
| Language: | English |
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2009
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