Purification and activity determination of ADAMTS-4 and ADAMTS-5 and their domain deleted mutants

Purification and activity determination of ADAMTS-4 and ADAMTS-5 and their domain deleted mutants

AA disintegrin-like and metalloproteinase with thrombospondin type-1 motifs-4 (ADAMTS-4) and ADAMTS-5 are zinc-dependent metalloproteinases that are involved in the maintenance of cartilage extracellular matrix (ECM) and are currently considered the major aggrecanases in the development of osteoarth...

Bibliográfalaš dieđut
Váldodahkkit:	Fowkes, MM, Lim, NH
Eará dahkkit:	Apte, SS
Materiálatiipa:	Book section
Giella:	English
Almmustuhtton:	Humana Press 2019

Geahča maid

Screening for selective ADAMTS-5 substrates to monitor proteinase activity
Dahkki: Fowkes, MM
Almmustuhtton: (2021)

Development of selective ADAMTS-5 peptide substrates to monitor proteinase activity
Dahkki: Fowkes, MM, et al.
Almmustuhtton: (2023)

Functional differences of the catalytic and non-catalytic domains in human ADAMTS-4 and ADAMTS-5 in aggrecanolytic activity.
Dahkki: Fushimi, K, et al.
Almmustuhtton: (2008)

Proteolytic activities of human ADAMTS-5: comparative studies with ADAMTS-4.
Dahkki: Gendron, C, et al.
Almmustuhtton: (2007)

Reactive-site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5: biological and structural implications.
Dahkki: Lim, N, et al.
Almmustuhtton: (2010)

The C-terminal domains of ADAMTS-4 and ADAMTS-5 promote association with N-TIMP-3.
Dahkki: Troeberg, L, et al.
Almmustuhtton: (2009)

ADAMTS4 and ADAMTS5 are upregulated early in the DMM model of murine OA
Dahkki: Burleigh, A, et al.
Almmustuhtton: (2009)

Engineering and expression of ADAMTS-4 and ADAMTS-5, proteolytic enzymes involved in osteoarthritis progression
Dahkki: Lauer-Fields, J, et al.
Almmustuhtton: (2005)

Serum Level of ADAMTS4 and ADAMTS8 in Patients with Psoriatic Arthritis
Dahkki: Irmak Icen Taskin, et al.
Almmustuhtton: (2020-12-01)

ADAMTS2 and ADAMTS14 can substitute for ADAMTS3 in adults for pro-VEGFC activation and lymphatic homeostasis
Dahkki: Laura Dupont, et al.
Almmustuhtton: (2022-04-01)

The ADAMTS/Fibrillin Connection: Insights into the Biological Functions of ADAMTS10 and ADAMTS17 and Their Respective Sister Proteases
Dahkki: Stylianos Z. Karoulias, et al.
Almmustuhtton: (2020-04-01)

Cleavage of Fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells
Dahkki: Fontanil, T, et al.
Almmustuhtton: (2017)

Genetic variants in ADAMTS13 as well as smoking are major determinants of plasma ADAMTS13 levels
Dahkki: Qianyi Ma, et al.
Almmustuhtton: (2017-06-01)

ADAMTS-5: The story so far
Dahkki: A J Fosang, et al.
Almmustuhtton: (2008-02-01)

Investigation of the endocytic pathway of ADAMTS-4
Dahkki: Owen, K, et al.
Almmustuhtton: (2009)

Low density lipoprotein receptor-related protein 1 (LRP1)-mediated endocytic clearance of a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4): functional differences of non-catalytic domains of ADAMTS-4 and ADAMTS-5 in LRP1 binding.
Dahkki: Yamamoto, K, et al.
Almmustuhtton: (2014)

Multiple domains of ADAMTS13 are targeted by autoantibodies against ADAMTS13 in patients with acquired idiopathic thrombotic thrombocytopenic purpura
Dahkki: X. Long Zheng, et al.
Almmustuhtton: (2010-09-01)

Regulation of ADAMTS Proteases
Dahkki: Keron W. J. Rose, et al.
Almmustuhtton: (2021-06-01)

Acquired thrombotic thrombocytopenic purpura: ADAMTS13 activity, anti-ADAMTS13 autoantibodies and risk of recurrent disease
Dahkki: Bernhard Lämmle, et al.
Almmustuhtton: (2008-02-01)

Disappearing acts of ADAMTS13
Dahkki: Jan Voorberg, et al.
Almmustuhtton: (2015-08-01)

Determination of ADAMTS13 and Its Clinical Significance for ADAMTS13 Supplementation Therapy to Improve the Survival of Patients with Decompensated Liver Cirrhosis
Dahkki: Masahito Uemura, et al.
Almmustuhtton: (2011-01-01)

Ocular pulse amplitude (OPA) in canine ADAMTS10-open-angle glaucoma (ADAMTS10-OAG)
Dahkki: Vanessa A. Raphtis, et al.
Almmustuhtton: (2023-12-01)

ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice
Dahkki: Naamah L. Zitomersky, et al.
Almmustuhtton: (2017-06-01)

Evidence for a role of anti-ADAMTS13 autoantibodies despite normal ADAMTS13 activity in recurrent thrombotic thrombocytopenic purpura
Dahkki: Rahel Froehlich-Zahnd, et al.
Almmustuhtton: (2012-02-01)

Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing.
Dahkki: Kashiwagi, M, et al.
Almmustuhtton: (2004)

ADAMTS proteases in cardiovascular physiology and disease
Dahkki: Salvatore Santamaria, et al.
Almmustuhtton: (2020-12-01)

Interleukin-1α induces ADAMTS-mediated aggrecanolysis in the bovine meniscus: evidence for a primary role of ADAMTS-4 in meniscus destruction
Dahkki: Lemke, Angelika K., et al.
Almmustuhtton: (2012)

ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission
Dahkki: Flora Peyvandi, et al.
Almmustuhtton: (2008-02-01)

Assay for ADAMTS-13 Activity with Flow Cytometric Readout
Dahkki: Jens Müller, et al.
Almmustuhtton: (2022-08-01)

The first deletion mutation in the TSP1-6 repeat domain of ADAMTS13 in a family with inherited thrombotic thrombocytopenic purpura
Dahkki: Roberta Palla, et al.
Almmustuhtton: (2009-02-01)

Genetic variation of aggrecanase-2 (ADAMTS5) in susceptibility to osteoarthritis
Dahkki: Xindie Zhou, et al.
Almmustuhtton: (2019-01-01)

ADAMTS7, a target in atherosclerosis, cooperates with its homolog ADAMTS12 to protect against myxomatous valve degeneration
Dahkki: Timothy J. Mead, et al.
Almmustuhtton: (2025-03-01)

Hemoglobin stimulates the expression of ADAMTS-5 and ADAMTS-9 by synovial cells: a possible cause of articular cartilage damage after intra-articular hemorrhage
Dahkki: Takuya Tajima, et al.
Almmustuhtton: (2017-11-01)

The Function and Roles of ADAMTS-7 in Inflammatory Diseases
Dahkki: Yuying Zhang, et al.
Almmustuhtton: (2015-01-01)

The Mechanism and Role of ADAMTS Protein Family in Osteoarthritis
Dahkki: Ting Li, et al.
Almmustuhtton: (2022-07-01)

Expression and prognosis of ADAMTS18 in different tumors
Dahkki: Wenfei Guo, et al.
Almmustuhtton: (2024-02-01)

ADAMTS Proteins and Vascular Remodeling in Aortic Aneurysms
Dahkki: Zakaria Mougin, et al.
Almmustuhtton: (2021-12-01)

ADAMTS-13 gene expression in antiphospholipid syndrome
Dahkki: Veysel Sabri Hançer, et al.
Almmustuhtton: (2011-09-01)

ADAMTS-13 gene expression in antiphospholipid syndrome
Dahkki: Veysel Sabri Hançer, et al.
Almmustuhtton: (2011-08-01)

Role of ADAM and ADAMTS metalloproteinases in airway diseases
Dahkki: Noel Agnes, et al.
Almmustuhtton: (2009-12-01)