Purification and activity determination of ADAMTS-4 and ADAMTS-5 and their domain deleted mutants

Purification and activity determination of ADAMTS-4 and ADAMTS-5 and their domain deleted mutants

AA disintegrin-like and metalloproteinase with thrombospondin type-1 motifs-4 (ADAMTS-4) and ADAMTS-5 are zinc-dependent metalloproteinases that are involved in the maintenance of cartilage extracellular matrix (ECM) and are currently considered the major aggrecanases in the development of osteoarth...

Bibliografski detalji
Glavni autori:	Fowkes, MM, Lim, NH
Daljnji autori:	Apte, SS
Format:	Book section
Jezik:	English
Izdano:	Humana Press 2019

Slični predmeti

Screening for selective ADAMTS-5 substrates to monitor proteinase activity
od: Fowkes, MM
Izdano: (2021)

Development of selective ADAMTS-5 peptide substrates to monitor proteinase activity
od: Fowkes, MM, i dr.
Izdano: (2023)

Functional differences of the catalytic and non-catalytic domains in human ADAMTS-4 and ADAMTS-5 in aggrecanolytic activity.
od: Fushimi, K, i dr.
Izdano: (2008)

Proteolytic activities of human ADAMTS-5: comparative studies with ADAMTS-4.
od: Gendron, C, i dr.
Izdano: (2007)

Reactive-site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5: biological and structural implications.
od: Lim, N, i dr.
Izdano: (2010)

The C-terminal domains of ADAMTS-4 and ADAMTS-5 promote association with N-TIMP-3.
od: Troeberg, L, i dr.
Izdano: (2009)

ADAMTS4 and ADAMTS5 are upregulated early in the DMM model of murine OA
od: Burleigh, A, i dr.
Izdano: (2009)

Engineering and expression of ADAMTS-4 and ADAMTS-5, proteolytic enzymes involved in osteoarthritis progression
od: Lauer-Fields, J, i dr.
Izdano: (2005)

Serum Level of ADAMTS4 and ADAMTS8 in Patients with Psoriatic Arthritis
od: Irmak Icen Taskin, i dr.
Izdano: (2020-12-01)

ADAMTS2 and ADAMTS14 can substitute for ADAMTS3 in adults for pro-VEGFC activation and lymphatic homeostasis
od: Laura Dupont, i dr.
Izdano: (2022-04-01)

The ADAMTS/Fibrillin Connection: Insights into the Biological Functions of ADAMTS10 and ADAMTS17 and Their Respective Sister Proteases
od: Stylianos Z. Karoulias, i dr.
Izdano: (2020-04-01)

Cleavage of Fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells
od: Fontanil, T, i dr.
Izdano: (2017)

Genetic variants in ADAMTS13 as well as smoking are major determinants of plasma ADAMTS13 levels
od: Qianyi Ma, i dr.
Izdano: (2017-06-01)

ADAMTS-5: The story so far
od: A J Fosang, i dr.
Izdano: (2008-02-01)

Investigation of the endocytic pathway of ADAMTS-4
od: Owen, K, i dr.
Izdano: (2009)

Low density lipoprotein receptor-related protein 1 (LRP1)-mediated endocytic clearance of a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4): functional differences of non-catalytic domains of ADAMTS-4 and ADAMTS-5 in LRP1 binding.
od: Yamamoto, K, i dr.
Izdano: (2014)

Multiple domains of ADAMTS13 are targeted by autoantibodies against ADAMTS13 in patients with acquired idiopathic thrombotic thrombocytopenic purpura
od: X. Long Zheng, i dr.
Izdano: (2010-09-01)

Regulation of ADAMTS Proteases
od: Keron W. J. Rose, i dr.
Izdano: (2021-06-01)

Acquired thrombotic thrombocytopenic purpura: ADAMTS13 activity, anti-ADAMTS13 autoantibodies and risk of recurrent disease
od: Bernhard Lämmle, i dr.
Izdano: (2008-02-01)

Thrombotic thrombocytopenic purpura with decreased level of ADAMTS-13 activity and increased level of ADAMTS-13 inhibitor in an adolescent
od: Eun Mi Yang, i dr.
Izdano: (2010-03-01)

Disappearing acts of ADAMTS13
od: Jan Voorberg, i dr.
Izdano: (2015-08-01)

ADAMTS expression in colorectal cancer.
od: Serafula Filou, i dr.
Izdano: (2015-01-01)

Determination of ADAMTS13 and Its Clinical Significance for ADAMTS13 Supplementation Therapy to Improve the Survival of Patients with Decompensated Liver Cirrhosis
od: Masahito Uemura, i dr.
Izdano: (2011-01-01)

Functional role of ADAMTS5 in adiposity and metabolic health.
od: Dries Bauters, i dr.
Izdano: (2018-01-01)

Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide
od: Salvatore Santamaria, i dr.
Izdano: (2021-01-01)

Ocular pulse amplitude (OPA) in canine ADAMTS10-open-angle glaucoma (ADAMTS10-OAG)
od: Vanessa A. Raphtis, i dr.
Izdano: (2023-12-01)

ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice
od: Naamah L. Zitomersky, i dr.
Izdano: (2017-06-01)

Evidence for a role of anti-ADAMTS13 autoantibodies despite normal ADAMTS13 activity in recurrent thrombotic thrombocytopenic purpura
od: Rahel Froehlich-Zahnd, i dr.
Izdano: (2012-02-01)

Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing.
od: Kashiwagi, M, i dr.
Izdano: (2004)

Interleukin-1α induces ADAMTS-mediated aggrecanolysis in the bovine meniscus: evidence for a primary role of ADAMTS-4 in meniscus destruction
od: Lemke, Angelika K., i dr.
Izdano: (2012)

ADAMTS proteases in cardiovascular physiology and disease
od: Salvatore Santamaria, i dr.
Izdano: (2020-12-01)

ADAM and ADAMTS Proteases in Hepatic Disorders
od: Dirk Schmidt-Arras, i dr.
Izdano: (2019-02-01)

ADAMTS-1 in abdominal aortic aneurysm.
od: Emina Vorkapic, i dr.
Izdano: (2017-01-01)

ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission
od: Flora Peyvandi, i dr.
Izdano: (2008-02-01)

In vivo N-Terminomics Highlights Novel Functions of ADAMTS2 and ADAMTS14 in Skin Collagen Matrix Building
od: Cédric Leduc, i dr.
Izdano: (2021-03-01)

Assay for ADAMTS-13 Activity with Flow Cytometric Readout
od: Jens Müller, i dr.
Izdano: (2022-08-01)

Crystal structure and substrate-induced activation of ADAMTS13
od: Anastasis Petri, i dr.
Izdano: (2019-08-01)

Genetic variation of aggrecanase-2 (ADAMTS5) in susceptibility to osteoarthritis
od: Xindie Zhou, i dr.
Izdano: (2019-01-01)

A transcriptional enhancer from the coding region of ADAMTS5.
od: Kristen K B Barthel, i dr.
Izdano: (2008-05-01)

The first deletion mutation in the TSP1-6 repeat domain of ADAMTS13 in a family with inherited thrombotic thrombocytopenic purpura
od: Roberta Palla, i dr.
Izdano: (2009-02-01)