Mechanistic insight into enzymatic glycosyl transfer with retention of configuration through analysis of glycomimetic inhibitors.

(Figure Presented) Structural "valid"-ation: The mechanism of enzyme-catalyzed glycosyl transfer with retention of anomeric configuration continues to baffle, a situation compounded by the lack of insightful 3-D structures of ternary enzyme complexes. Synthesis and multi-dimensional kineti...

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Bibliographic Details
Main Authors: Errey, J, Lee, S, Gibson, R, Martinez Fleites, C, Barry, C, Jung, P, O'Sullivan, A, Davis, B, Davies, G
Format: Journal article
Language:English
Published: 2010