Purification of DNA repair protein complexes from mammalian cells
Cells possess multiple DNA repair pathways to tackle a variety of DNA lesions. Often, DNA repair proteins function as large protein complexes. Here, we describe a protocol to purify DNA repair protein complexes from nuclei of mammalian cells. The method permits purification of protein complexes cont...
Main Authors: | Liang, C-C, Cohn, MA |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2021
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