Clinico-pathological features and p53 expression in left-sided sporadic colorectal cancers with and without microsatellite instability.

Defects in mismatch repair (MMR) can result in the development of a 'mutator phenotype', manifest as an increase in DNA replication errors (RERs). Patients with hereditary non-polyposis colorectal cancer (HNPCC) have germline mutations in MMR genes. These patients develop carcinomas of the...

詳細記述

書誌詳細
主要な著者: Ilyas, M, Tomlinson, I, Novelli, MR, Hanby, A, Bodmer, W, Talbot, I
フォーマット: Journal article
言語:English
出版事項: 1996