Clinico-pathological features and p53 expression in left-sided sporadic colorectal cancers with and without microsatellite instability.

Clinico-pathological features and p53 expression in left-sided sporadic colorectal cancers with and without microsatellite instability.

Defects in mismatch repair (MMR) can result in the development of a 'mutator phenotype', manifest as an increase in DNA replication errors (RERs). Patients with hereditary non-polyposis colorectal cancer (HNPCC) have germline mutations in MMR genes. These patients develop carcinomas of the...

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Bibliographic Details
Main Authors:	Ilyas, M, Tomlinson, I, Novelli, MR, Hanby, A, Bodmer, W, Talbot, I
Format:	Journal article
Language:	English
Published:	1996

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