Role of T cells in inflammation caused by adenovirus vectors in the brain.

In many organs, E1-deleted human adenovirus vectors trigger antiviral T cell responses which limit the duration of vector-encoded gene expression. When injected into the brain, however, long-term expression is possible in spite of the ensuing inflammatory response. To examine the role of T cells in...

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Bibliographic Details
Main Authors: Byrnes, A, Wood, M, Charlton, H
Format: Journal article
Language:English
Published: 1996