Role of T cells in inflammation caused by adenovirus vectors in the brain.
In many organs, E1-deleted human adenovirus vectors trigger antiviral T cell responses which limit the duration of vector-encoded gene expression. When injected into the brain, however, long-term expression is possible in spite of the ensuing inflammatory response. To examine the role of T cells in...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
1996
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