Modeling of dynamic cerebrovascular reactivity to spontaneous and externally induced CO2 fluctuations in the human brain using BOLD-fMRI

In this work, we investigate the regional characteristics of the dynamic interactions between arterial CO2 and BOLD (dynamic cerebrovascular reactivity - dCVR) during normal breathing and hypercapnic, externally induced step CO2 challenges. To obtain dCVR curves at each voxel, we use a custom set of...

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Bibliographic Details
Main Authors: Prokopiou, PC, Pattinson, KTS, Wise, RG, Mitsis, GD
Format: Journal article
Published: Elsevier 2018