Loss of zolpidem efficacy in the hippocampus of mice with the GABAA receptor gamma2 F77I point mutation.

Loss of zolpidem efficacy in the hippocampus of mice with the GABAA receptor gamma2 F77I point mutation.

Zolpidem is a hypnotic benzodiazepine site agonist with some gamma-aminobutyric acid (GABA)(A) receptor subtype selectivity. Here, we have tested the effects of zolpidem on the hippocampus of gamma2 subunit (gamma2F77I) point mutant mice. Analysis of forebrain GABA(A) receptor expression with immuno...

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Detalhes bibliográficos
Main Authors: Cope, D, Halbsguth, C, Karayannis, T, Wulff, P, Ferraguti, F, Hoeger, H, Leppä, E, Linden, A, Oberto, A, Ogris, W, Korpi, E, Sieghart, W, Somogyi, P, Wisden, W, Capogna, M
Formato: Journal article
Idioma:English
Publicado em: 2005

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