Differentially expressed, variant U1 snRNAs regulate gene expression in human cells

Human U1 small nuclear (sn)RNA, required for splicing of pre-mRNA, is encoded by genes on chromosome 1 (1p36). Imperfect copies of these U1 snRNA genes, also located on chromosome 1 (1q12-21), were thought to be pseudogenes. However, many of these "variant" (v)U1 snRNA genes produce fully...

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Bibliographic Details
Main Authors: O'Reilly, D, Dienstbier, M, Cowley, S, Vazquez, P, Drozdz, M, Taylor, S, James, W, Murphy, S
Format: Journal article
Language:English
Published: Cold Spring Harbor Laboratory Press 2013