Radiation response and combination target discovery in a novel model of rectal cancer

Radiation response and combination target discovery in a novel model of rectal cancer

<p>Rectal cancer is typically treated with radiotherapy, with or without chemotherapy, prior to surgical resection of the tumour. However, in patients that respond poorly to radiation, tumours largely lack significant immune cells within the surrounding milieu and present with a CAF-rich strom...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteur:	Beach, CJ
Andere auteurs:	Leedham, S
Formaat:	Thesis
Taal:	English
Gepubliceerd in:	2024
Onderwerpen:	Rectum > Cancer Radiotherapy Oncology, Experimental Cancer > Immunotherapy

Gelijkaardige items

Evaluation of Quality of Life, Depression and Anxiety in Patients with Rectal Cancer Receiving Radiotherapy
door: Feryal Karaca, et al.
Gepubliceerd in: (2020-02-01)

Immunogenomic pathways associated with cytotoxic lymphocyte infiltration and survival in colorectal cancer
door: Yuanyuan Shen, et al.
Gepubliceerd in: (2020-02-01)

On the trail of CBCT-guided adaptive rectal boost radiotherapy, does daily delineation require a radiation oncologist?
door: Julien Pierrard, et al.
Gepubliceerd in: (2024-12-01)

Efficacy of radiotherapy in patients with rectal cancer undergoing chemotherapy and surgery: a retrospective study based on the SEER database
door: WANG Anjun, et al.
Gepubliceerd in: (2023-03-01)

Assessment of Variations in Serum Testosterone, Follicle Stimulating Hormone, and Luteinizing Hormone Levels in Patients Receiving Radiotherapy for Rectal Cancer
door: Abhishek Krishna, et al.
Gepubliceerd in: (2022-04-01)

Immune Checkpoint Inhibition as a Strategy in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer
door: Catherine R. Hanna, et al.
Gepubliceerd in: (2021-05-01)

Treatment of advanced rectal cancers: Cylindrical abdominoperineal excision of rectum
door: Nirmal Lamichhane, et al.
Gepubliceerd in: (2018-12-01)

Influence of neoadjuvant radiotherapy combined with immunotherapy on minimally invasive surgeries for rectal cancer
door: YANG Yingchi, PANG Kai, ZHANG Zhongtao
Gepubliceerd in: (2023-05-01)

Dose-escalated radiotherapy to 82 Gy for prostate cancer following insertion of a peri-rectal hydrogel spacer: 3-year outcomes from a phase II trial
door: Andrew W. See, et al.
Gepubliceerd in: (2022-07-01)

Initial results of treatment of rectal cancer using the neoadjuvant treatment
door: Marić Zdravko, et al.
Gepubliceerd in: (2014-01-01)

Cellular adaptations to low extracellular pH in the microenvironment of colorectal cancer and other solid tumours
door: White, B
Gepubliceerd in: (2024)

Comparison of transanal versus laparoscopic total mesorectal excision in low rectal cancer
door: Seyed Vahid Hosseini, et al.
Gepubliceerd in: (2020-12-01)

Combining Radiotherapy and Immunotherapy in Metastatic Breast Cancer: Current Status and Future Directions
door: Steven David, et al.
Gepubliceerd in: (2022-03-01)

New rectum dose surface mapping methodology to identify rectal subregions associated with toxicities following prostate cancer radiotherapy
door: Artemis Bouzaki, et al.
Gepubliceerd in: (2025-01-01)

2017 WSES guidelines on colon and rectal cancer emergencies: obstruction and perforation
door: Michele Pisano, et al.
Gepubliceerd in: (2018-08-01)

Case Report: Mammary and rectal metastases from an ovarian cancer: report of two cases and review of literature [v2; ref status: indexed, http://f1000r.es/4wh]
door: Mounia Amzerin, et al.
Gepubliceerd in: (2014-12-01)

Durvalumab (MEDI 4736) in combination with extended neoadjuvant regimens in rectal cancer: a study protocol of a randomised phase II trial (PRIME-RT)
door: Catherine R. Hanna, et al.
Gepubliceerd in: (2021-08-01)

A study on the variation of bladder and rectal doses with respiration in intracavitary brachytherapy for cervix cancer
door: Singh Karuna, et al.
Gepubliceerd in: (2010-04-01)

Anorectal function and outcomes after transanal minimally invasive surgery for rectal tumors
door: Feza Y Karakayali, et al.
Gepubliceerd in: (2015-01-01)

Short-course radiation followed by mFOLFOX-6 plus avelumab for locally-advanced rectal adenocarcinoma
door: Ali Shamseddine, et al.
Gepubliceerd in: (2020-09-01)

Contribution of Endorectal Ultrasound, Magnetic Resonance Imaging and Positron Emission Tomography to Operation Strategy in Rectal Cancer
door: Yurdakul Deniz Fırat, et al.
Gepubliceerd in: (2021-03-01)

[18F]Fluoromisonidazole PET in rectal cancer
door: Tanuj Puri, et al.
Gepubliceerd in: (2017-09-01)

Effectiveness of bladder filling control during online MR-guided adaptive radiotherapy for rectal cancer
door: Xi Feng, et al.
Gepubliceerd in: (2023-08-01)

Long-term results of surgical treatment of a locally advanced rectal cancer using extrafascial principle of dissection
door: P. V. Tsarkov, et al.
Gepubliceerd in: (2010-08-01)

Long-course chemoradiation versus short-course radiation for rectal cancer and overall comparison
door: Subhrokanti Kundu
Gepubliceerd in: (2014-05-01)

LONG-TERM OUTCOMES OF SPINKTER-SPARING SURGERIES IN MID- AND LOWER AMPULLARY RECTAL CANCER: QUALITY OF LIFE AND SURVIVAL OF PATIENTS
door: A. A. Medvednikov, et al.
Gepubliceerd in: (2020-03-01)

Rectal dosimetry in intracavitary applications of cervix carcinoma: Comparison of two methods
door: Baucal Milutin, et al.
Gepubliceerd in: (2002-01-01)

Autosegmentation based on different-sized training datasets of consistently-curated volumes and impact on rectal contours in prostate cancer radiation therapy
door: Caroline Elisabeth Olsson, et al.
Gepubliceerd in: (2022-04-01)

Is prostate cancer radiotherapy using implantable rectum spacers safe and effective in inflammatory bowel disease patients?
door: Ben G.L. Vanneste, et al.
Gepubliceerd in: (2021-03-01)

The future of cancer treatment: combining radiotherapy with immunotherapy
door: Gunjan Dagar, et al.
Gepubliceerd in: (2024-07-01)

Applicability of a pathological complete response magnetic resonance-based radiomics model for locally advanced rectal cancer in intercontinental cohort
door: Luca Boldrini, et al.
Gepubliceerd in: (2022-04-01)

Disseminated lung cancer presenting as a rectal mass
door: Mia M. Noergaard, et al.
Gepubliceerd in: (2016-09-01)

Incidence of permanent stoma after rectal cancer surgery and its risk factors
door: İsmail Cem Eray, et al.
Gepubliceerd in: (2019-12-01)

The study of a rectal dose in cervical carcinoma: High dose rate brachytherapy calculated based on the ICRU Report 38 Recommendation and Multiple Points Calculation in Lampang Cancer Hospital
door: Jumneanphan Reunsri, et al.
Gepubliceerd in: (2013-01-01)

Hyperacute Radiation Pneumonitis after Severe irAE
door: Yang Chou, et al.
Gepubliceerd in: (2024-04-01)

Cryptosporidiosis and Colorectal Cancer
door: Sim Sai Tin, et al.
Gepubliceerd in: (2015-09-01)

MRI of rectal cancer—relevant anatomy and staging key points
door: Inês Santiago, et al.
Gepubliceerd in: (2020-09-01)

Radiologic Report for Magnetic Resonance Imaging of Rectal Cancer before Treatment
door: Byung Geon Park, et al.
Gepubliceerd in: (2019-05-01)

Editorial: The role of epigenetic modification in radiotherapy and immuno-oncology in cancer: from bench to clinical application
door: Hon-Yi Lin, et al.
Gepubliceerd in: (2023-05-01)

Câncer do reto médio: avaliação do procedimento cirúrgico
door: José Hyppólito da Silva, et al.