Increased invasive behaviour in cutaneous squamous cell carcinoma with loss of basement-membrane type VII collagen.

Type VII collagen (ColVII) is the main component of anchoring fibrils, attachment structures within the lamina densa of the basement membrane that are responsible for attachment of the epidermis to the dermis in skin. Mutations in the human ColVII gene, COL7A1, cause the severe inherited blistering...

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Bibliographic Details
Main Authors: Martins, V, Vyas, J, Chen, M, Purdie, K, Mein, C, South, A, Storey, A, McGrath, J, O'Toole, E
Format: Journal article
Language:English
Published: 2009