Mouse H-2(k)-restricted cytotoxic T cells recognize antigenic determinants in both the HA1 and HA2 subunits of the influenza A/PR/8/34 hemagglutinin
We have constructed two chimeric influenza hemagglutinin (HA) genes in which the HA1 and HA2 subunits of the HA molecule have been interchanged between influenza A/PR/8/34 (H1 subtype) and A/NT/60/68 (H3 subtype). These genes were used to construct recombinant vaccinia viruses that expressed intact...
मुख्य लेखकों: | Gould, K, Scotney, H, Townsend, A, Bastin, J, Brownlee, G |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
1987
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समान संसाधन
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A 15 amino acid fragment of influenza nucleoprotein synthesized in the cytoplasm is presented to class I-restricted cytotoxic T lymphocytes.
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