Immunohistological screening in the selection of monoclonal antibodies: the use of isotype-specific antiglobulins.

This paper describes the use of the immunoperoxidase technique for the screening of rat hybridoma culture supernatants on tissue sections. By combining the avidin-biotin system with mouse monoclonal antibodies specific to different rat immunoglobulin isotypes, it is possible to resolve the specifici...

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Bibliographic Details
Main Authors: Aqel, N, Clark, M, Cobbold, S, Waldmann, H
Format: Journal article
Language:English
Published: 1984