MPL mutations in myeloproliferative disorders: analysis of the PT-1 cohort.

Activating mutations of MPL exon 10 have been described in a minority of patients with idiopathic myelofibrosis (IMF) or essential thrombocythemia (ET), but their prevalence and clinical significance are unclear. Here we demonstrate that MPL mutations outside exon 10 are uncommon in platelet cDNA an...

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Bibliographic Details
Main Authors: Beer, P, Campbell, P, Scott, L, Bench, A, Erber, W, Bareford, D, Wilkins, B, Reilly, J, Hasselbalch, H, Bowman, R, Wheatley, K, Buck, G, Harrison, C, Green, A
Format: Journal article
Language:English
Published: 2008