DarTG is a novel toxin-antitoxin system that catalyses the reversible ADP-ribosylation of DNA

DarTG is a novel toxin-antitoxin system that catalyses the reversible ADP-ribosylation of DNA

The discovery and study of toxin-antitoxin (TA) systems helps us advance our understanding of the strategies prokaryotes employ to regulate cellular processes related to the general stress response, such as defense against phages, growth control, biofilm formation, persistence and programmed cell de...

Полное описание

Библиографические подробности
Главные авторы:	Ariza, A, Jankevicius, G, Ahel, M, Ahel, I
Формат:	Conference item
Опубликовано:	Microbiology Society 2017

Схожие документы

The DarTG toxin-antitoxin system provides phage defence by ADP-ribosylating viral DNA
по: LeRoux, Michele, и др.
Опубликовано: (2023)

Phages carry orphan antitoxin-like enzymes to neutralize the DarTG1 toxin-antitoxin defense system
по: Anna Johannesman, и др.
Опубликовано: (2025-02-01)

Reversible mono-ADP-ribosylation of DNA breaks.
по: Munnur, D, и др.
Опубликовано: (2017)

Sporadic phage defense in epidemic Vibrio cholerae mediated by the toxin-antitoxin system DarTG is countered by a phage-encoded antitoxin mimic
по: Kishen M. Patel, и др.
Опубликовано: (2024-10-01)

Specificity of DNA ADP-Ribosylation Reversal by NADARs
по: Bara Cihlova, и др.
Опубликовано: (2024-04-01)

Viral macro domains reverse protein ADP-ribosylation.
по: Li, C, и др.
Опубликовано: (2016)

DNA ADP-ribosylation stalls replication and is reversed by RecF-mediated homologous recombination and nucleotide excision repair
по: Lawarée, E, и др.
Опубликовано: (2020)

Reversible ADP-ribosylation of RNA
по: Munnur, D, и др.
Опубликовано: (2019)

DNA ADP-Ribosylation Stalls Replication and Is Reversed by RecF-Mediated Homologous Recombination and Nucleotide Excision Repair
по: Emeline Lawarée, и др.
Опубликовано: (2020-02-01)

Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling
по: Pietro Fontana, и др.
Опубликовано: (2023-06-01)

Specificity of reversible ADP-ribosylation and regulation of cellular processes
по: Crawford, K, и др.
Опубликовано: (2017)

Serine ADP-ribosylation reversal by the hydrolase ARH3
по: Fontana, P, и др.
Опубликовано: (2017)

Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal
по: Rack, JGM, и др.
Опубликовано: (2021)

Serine ADP-ribosylation reversal by the hydrolase ARH3
по: Pietro Fontana, и др.
Опубликовано: (2017-06-01)

The Making and Breaking of Serine-ADP-Ribosylation in the DNA Damage Response
по: Kira Schützenhofer, и др.
Опубликовано: (2021-11-01)

The DarT/DarG Toxin–Antitoxin ADP-Ribosylation System as a Novel Target for a Rational Design of Innovative Antimicrobial Strategies
по: Giuliana Catara, и др.
Опубликовано: (2023-02-01)

Studying catabolism of protein ADP-Ribosylation
по: Palazzo, L, и др.
Опубликовано: (2017)

ADP-ribosylation: new facets of an ancient modification
по: Palazzo, L, и др.
Опубликовано: (2017)

(ADP-ribosyl)hydrolases: structure, function, and biology
по: Rack, JGM, и др.
Опубликовано: (2020)

Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal
по: Johannes Gregor Matthias Rack, и др.
Опубликовано: (2021-07-01)

Beyond protein modification: the rise of non-canonical ADP-ribosylation
по: Schuller, M, и др.
Опубликовано: (2022)

Reanalysis of phosphoproteomics data uncovers ADP-ribosylation sites.
по: Matic, I, и др.
Опубликовано: (2012)

Serine is the major residue for ADP-ribosylation upon DNA damage
по: Palazzo, L, и др.
Опубликовано: (2018)

Serine is the major residue for ADP-ribosylation upon DNA damage
по: Luca Palazzo, и др.
Опубликовано: (2018-02-01)

HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation
по: Suskiewicz, MJ, и др.
Опубликовано: (2020)

The role of ADP-ribosylation in regulating DNA interstrand crosslink repair
по: Gunn, A, и др.
Опубликовано: (2016)

Streptomyces coelicolor macrodomain hydrolase SCO6735 cleaves thymidine-linked ADP-ribosylation of DNA
по: Hloušek-Kasun, A, и др.
Опубликовано: (2022)

Interplay of histone marks with serine ADP-ribosylation
по: Bartlett, E, и др.
Опубликовано: (2018)

Reversing ADP-ribosylation
по: Giuliana Katharina Moeller, и др.
Опубликовано: (2017-08-01)

Deregulated DNA ADP-ribosylation impairs telomere replication
по: Wondisford, AR, и др.
Опубликовано: (2024)

Streptomyces coelicolor macrodomain hydrolase SCO6735 cleaves thymidine-linked ADP-ribosylation of DNA
по: Andrea Hloušek-Kasun, и др.
Опубликовано: (2022-01-01)

(ADP-ribosyl)hydrolases: Structural basis for differential substrate recognition and inhibition
по: Rack, J, и др.
Опубликовано: (2018)

DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on protein substrates
по: Zhu, K, и др.
Опубликовано: (2022)

Arginine-specific mono ADP-ribosylation in vitro of antimicrobial peptides by ADP-ribosylating toxins.
по: Marta Castagnini, и др.
Опубликовано: (2012-01-01)

Suppression of ADP-ribosylation reversal triggers cell vulnerability to alkylating agents
по: Rocco Caggiano, и др.
Опубликовано: (2025-01-01)

Molecular tools for the study of ADP-ribosylation: a unified and versatile method to synthesise native mono-ADP-ribosylated peptides
по: Voorneveld, J, и др.
Опубликовано: (2021)

Serine ADP-Ribosylation Depends on HPF1
по: Bonfiglio, J, и др.
Опубликовано: (2017)

Monitoring poly(ADP-ribosyl)glycohydrolase activity with a continuous fluorescent substrate
по: Drown, B, и др.
Опубликовано: (2018)

MacroD1 is a promiscuous ADP-ribosyl hydrolase localized to mitochondria
по: Agnew, T, и др.
Опубликовано: (2018)

ENPP1 processes protein ADP-ribosylation in vitro.
по: Palazzo, L, и др.
Опубликовано: (2016)