Signalling cross talk of the HIF system: involvement of the FIH protein.

Signalling cross talk of the HIF system: involvement of the FIH protein.

Cellular and systemic oxygen homeostasis is regulated by an oxygen-sensitive signalling pathway centred on a transcription factor known as Hypoxia Inducible Factor (HIF). Regulation of HIF activity and protein stability is mediated by a family of hydroxylases that act as oxygen sensors due to the de...

書誌詳細
主要な著者:	Coleman, M, Ratcliffe, P
フォーマット:	Journal article
言語:	English
出版事項:	2009

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