When half a glass of STAT3 is just not enough.

In this issue of Blood, Bocchini et al report a novel mechanism by which STAT3 mutations result in an unstable protein and give rise to a reduction in STAT3 signalling, suggesting that pathogenic mutations do not always confer dominant negative effects via forming of non-functional STAT3 dimers but...

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Bibliographic Details
Main Authors: Laurence, A, Uhlig, H
Format: Journal article
Language:English
Published: American Society of Hematology 2016