When half a glass of STAT3 is just not enough.
In this issue of Blood, Bocchini et al report a novel mechanism by which STAT3 mutations result in an unstable protein and give rise to a reduction in STAT3 signalling, suggesting that pathogenic mutations do not always confer dominant negative effects via forming of non-functional STAT3 dimers but...
Main Authors: | Laurence, A, Uhlig, H |
---|---|
Format: | Journal article |
Language: | English |
Published: |
American Society of Hematology
2016
|
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