Structures of the Ets protein DNA-binding domains of transcription factors Etv1, Etv4, Etv5, and Fev determinants of DNA binding and redox regulation by disulfide bond formation.
Ets transcription factors, which share the conserved Ets DNAbinding domain, number nearly 30 members in humans and are particularly involved in developmental processes. Their deregulation following changes in expression, transcriptional activity, or by chromosomal translocation plays a critical role...
| Main Authors: | , , , , |
|---|---|
| Formato: | Journal article |
| Idioma: | English |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
|