Mechanistic modeling of primaquine pharmacokinetics, gametocytocidal activity, and mosquito infectivity
<p>Clinical studies have shown that adding a single 0.25 mg base/kg dose of primaquine to standard antimalarial regimens rapidly sterilizes <em>Plasmodium falciparum</em> gametocytes. However, the mechanism of action and overall impact on malaria transmission is still unknown. Usin...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Wiley
2022
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