A COVID moonshot: assessment of ligand binding to the SARS-CoV-2 main protease by saturation transfer difference NMR spectroscopy

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological cause of the coronavirus disease 2019, for which no efective antiviral therapeutics are available. The SARS-CoV-2 main protease (Mpro) is essential for viral replication and constitutes a promising therapeutic target. Ma...

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Bibliographic Details
Main Authors: Kantsadi, AL, Cattermole, E, Matsoukas, M-T, Spyroulias, G, Vakonakis, I
Format: Journal article
Language:English
Published: Springer Nature 2021