Development of chemogenetic methodology to investigate cortical mechanisms of cognition

<p>DREADDs (designer receptors exclusively activated by designer drugs) are virally mediated engineered muscarinic receptors that no longer bind their endogenous ligand acetylcholine but instead bind the clozapine metabolite, clozapine-N-oxide (CNO). These receptors are a very useful research...

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Bibliographic Details
Main Author: Rotariu, SM
Other Authors: Sharp, T
Format: Thesis
Language:English
Published: 2019