Single-cell RNAseq profiling of early heart developmental physiology

The heart is the first organ to form and function during mammalian development. Recently we established that in the mouse embryo, spontaneous asynchronous calcium oscillations (SACOs) occour in the cardiac crescent prior to the onset of cardiac contractions. Blocking Sodium Calcium Exchanger (NCX1)...

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書誌詳細
主要な著者: Miranda, AMA, Tyser, RCV, Riley, PR, Scialdone, A, Marioni, J, Srinivas, S
フォーマット: Conference item
出版事項: Elsevier 2017
その他の書誌記述
要約:The heart is the first organ to form and function during mammalian development. Recently we established that in the mouse embryo, spontaneous asynchronous calcium oscillations (SACOs) occour in the cardiac crescent prior to the onset of cardiac contractions. Blocking Sodium Calcium Exchanger (NCX1) function inhibits these oscillations and cardiac differentiation.