The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time.

In Drosophila cells cyclin B is normally degraded in two phases: (a) destruction of the spindle-associated cyclin B initiates at centrosomes and spreads to the spindle equator; and (b) any remaining cytoplasmic cyclin B is degraded slightly later in mitosis. We show that the APC/C regulators Fizzy (...

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Príomhchruthaitheoirí: Raff, J, Jeffers, K, Huang, J
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2002